Definition of Eye Drops
Eye drops are sterile preparations in the form of a solution or suspension which is used by dripping the drug on the mucous membranes around the eyelid from the eyeball. They can contain antimicrobial substances such as antibiotics, anti-inflammatory ingredients such as corticosteroids, medications such mioti fisostigmin midriatik sulfate or drugs such as atropine sulfate

Solution of the eyes (colluria / singular collyrium)
Drugs are inserted into the eye should be formulated and prepared with consideration given to the tonicity, pH, stability, viscosity and sterilization. Sterilization is desirable because the cornea and anterior chamber network nodes is a good medium for microorganisms and the entry of contaminated eye solutions into the eyes of trauma due to accidents or surgery can cause vision loss.

Terms of Good Eye Drops
The factors below will be most important in the preparation of a eye drop:
  1. Precision and cleanliness in the preparation of the solution; included free of foreign particles
  2. The sterility of the end of collyrium and the presence of antimicrobial agents effective for inhibiting the growth of many microorganisms during use of the preparation;
  3. Isotonicity of the solution;
  4. Appropriate pH in the carrier to produce an optimum stability
  5. The preparation of eye drops does not irritate the eyes
Sterilization is desirable because the cornea and anterior chamber network nodes is a good medium for the growth of microorganisms and the entry of contaminated eye fluid in the eye by accident trauma or surgery can cause vision loss.



The Advantages Eye Drops
  • In general, the aqueous solution is more stable than the ointment, though ointment with fat-soluble drug is better absorbed than solution / ointment which drug soluble in water.
  • Not disturbing visions when used
  • eye ointment generally produces a greater bioavailability than the aqueous solution.

The Disadvantages Eye Drops
  • relatively, had short contact time between drug and absorbed surface.
  • Bioavailability of eye drugs approved worse if the solution is used topically for most drugs is less than 1-3% of the dose that is inserted through the cornea to the anterior chamber. Since drug bioavailability very slow, the patient adhere to the rules and techniques of proper usage.


Use of Eye Drops
  • Wash hands
  • With one hand, gently pull the lower eyelid
  • If the dropping applicator separated apart, hit the rubber once when the dropper is inserted into the bottle to bring the solution into the dropper
  • Place the dropper above the eye, drops a drug into the lower eyelid while looking up do not touch dropper to eye or finger.
  • Release the eyelid, try to keep the eyes open and do not blink at least 30 seconds
  • If the dropping applicator separated apart, put back on the bottle and cover tightly
  • Never use eye drops that have become discolored
  • If you have more than one bottle of the same drops, open only one bottle
  • If you use more than one type of drops at the same time, wait several minutes before using other eye drops
  • After using the eye drops do not close your eyes too tight and not blink more often than usual because it can eliminate the drugs work.

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