The Operating Process of Blister Packaging Machine for Pharmaceutical Products

Blister packaging offers many advantages to the industry and to the public, and the machinery will continue to support this proven form of pharmaceutical packaging. Improvements in the form, materials, and machinery for blister packaging will continue to increase the applicability of this method for containing and distributing pharmaceutical products. Figure 1 shows an example of a blister packaging machine.

 The sequence involves :
  • heating the plastic
  • plastic thermoforming into blister cavities
  • loading the blister with the product
  • placing lidding material over the blister
  • heat-sealing the package
 There are 2 main types of blisterpacking machine :
  1. the continuously operating line
  2. the intermittently operating line

Plastic for Pharmaceutical Packaging : Thermosets and Thermoplastics

• Phenol Formaldehyde
• Urea Formaldehyde
• Melamine Formaldehyde

Melamine Formaldehyde
• Good-to-excellent dimensional stability
• When used in the manufacture of closures, high torque strength and good impact strength.
• Good resistance to oils, grease, and many organic solvent

Phenol Formaldehyde
• Good scratch-resistant parts.
• Very low shrinkage and low water-absorption properties

Urea Formaldehyde
• Good dimensional stability as well as good strength properties
• Highly rigid and provide good resistance to alcohols,oils, grease, and some weak acids.
• Use for injection-molded heads for collapsible tubes used to contai liquid-based topical product.

Plastic for Pharmaceutical Packaging

A plastic is a material that contains an essential ingredient one or more polymeric organic substances of large molecular weight. Plastic Used as container for the product and as secondary packaging.

Advantages of plastic:
• Flexible and not easily broken
• Low density and light in weight
• Are cheap

Disadvantages of plastic :
• They are not as chemically inert as Type I glass
• They are not as impermeable to gas and vapour as glass
• They may posses an electrostatic charge which will attract particles
• Used for many types of pack include ng rigid bottles for tablets and capsules, squeezable bottles for eye drops and nasal sprays, jars, flexible tubes and strip and blister packs.